| Tackles |
| Game |
| 1. | 27 | Dave Wyman | at California • 1986 |
| 2. | 23 | Don Parish | vs. Oregon State • 1968 |
| | 23 | Don Parish | at USC • 1969 |
| 4. | 22 | Pat Preston | at Washington State • 1968 |
| | 22 | Gordy Ceresino | vs. LSU • 1977 |
| 6. | 21 | Gordon Riegel | at Washington State • 1972 |
| 7. | 20 | Dave Wyman | vs. Washington • 1986 |
| | 20 | Pat Moore | at Washington State • 1972 |
| | 20 | Jim Merlo | vs. Oregon State • 1972 |
| | 20 | Jim Merlo | at Washington State • 1972 |
| | 20 | Gordy Ceresino | vs. Georgia • 1978 |
| | | | |
| Season |
| 1. | 196 | Gordy Ceresino | 1977 |
| 2. | 173 | Dave Wyman | 1986 |
| 3. | 167 | Gordy Ceresino | 1978 |
| 4. | 164 | Jim Merlo | 1972 |
| 5. | 159 | Gordy Ceresino | 1976 |
| 6. | 155 | Jono Tunney | 1988 |
| 7. | 154 | Drew Palin | 1974 |
| 8. | 150 | Gordon Riegel | 1974 |
| 9. | 144 | Dave Wyman | 1983 |
| 10. | 143 | Don Parish | 1968 |
| | | | |
| Career |
| 1. | 571 | Gordy Ceresino | 1975-78 |
| 2. | 462 | Dave Wyman | 1982-84, 86 |
| 3. | 430 | Jono Tunney | 1987-90 |
| 4. | 394 | Matt Soderlund | 1982-85 |
| 5. | 355 | Don Parish | 1967-69 |
| 6. | 353 | Shayne Skov | 2009-13 |
| 7. | 348 | Chuck Evans | 1976-79 |
| 8. | 347 | Duncan McColl | 1974-76 |
| 9. | 332 | Chris Draft | 1994-97 |
| 10. | 309 | Pat Preston | 1967-69 |
| | | | |
| Tackles for Loss |
| Season |
| 1. | 28 | Ron George | 1990 |
| 2. | 26 | Duncan McColl | 1975 |
| | 26 | Ron George | 1992 |
| 4. | 24 | Kailee Wong | 1996 |
| 5. | 23.5 | Trent Murphy | 2013 |
| 6. | 23 | Duncan McColl | 1976 |
| 7. | 22 | Kailee Wong | 1997 |
| | 22 | Rob Hinckley | 1988 |
| 9. | 20 | Willie Howard | 1999 |
| | 20 | Riall Johnson | 2000 |
| | | | |
| Career |
| 1. | 72 | Ron George | 1990-92 |
| 2. | 57 | Duncan McColl | 1974-76 |
| 3. | 54 | Kailee Wong | 1994-97 |
| 4. | 53 | Riall Johnson | 1997-00 |
| 5. | 52.5 | Trent Murphy | 2010-13 |
| 6. | 50.5 | Chase Thomas | 2009-12 |
| 7. | 50 | Garin Veris | 1981-84 |
| 8. | 49 | David Garnett | 1989-92 |
| 9. | 44 | Chuck Evans | 1976-79 |
| 10. | 41 | Willie Howard | 1997-00 |
| | | | |
| Sacks |
| Game |
| 1. | 5 | Riall Johnson | vs. Washington State • 1999 |
| | | | |
| Season |
| 1. | 17 | Duncan McColl | 1976 |
| 2. | 15 | Ron George | 1992 |
| | 15 | Riall Johnson | 2000 |
| | 15.0 | Trent Murphy | 2013 |
| 5. | 14 | Kailee Wong | 1996 |
| | 14 | Riall Johnson | 1999 |
| 7. | 13 | Rob Hinckley | 1988 |
| 8. | 12 | Kailee Wong | 1997 |
| 9. | 10 | Ron George | 1990 |
| | 10 | Willie Howard | 1999 |
| | 10 | Jon Alston | 2004 |
| | 10.0 | Trent Murphy | 2012 |
| | | | |
| Career |
| 1. | 36 | Riall Johnson | 1997-00 |
| 2. | 33 | Ron George | 1990-92 |
| 3. | 32.5 | Trent Murphy | 2010-13 |
| 4. | 28 | Kailee Wong | 1994-97 |
| 5. | 27.5 | Chase Thomas | 2009-12 |
| 6. | 25 | Duncan McColl | 1974-76 |
| | 25 | Garin Veris | 1981-84 |
| 8. | 22.5 | Willie Howard | 1997-00 |
| 9. | 21.5 | Carl Hansen | 1994-97 |
| | 21.5 | Jon Alston | 2002-05 |
| | | | |
| Interceptions |
| Game |
| 1. | 4 | Bobby Grayson | vs. Washington • 1934 |
| 2. | 3 | Tim Smith | at Arizona • 1999 |
| | 3 | Tim Smith | vs. Washington State • 1998 |
| | 3 | Leroy Pruitt | at Northwestern • 1994 |
| | 3 | Toi Cook | vs. San Jose State • 1986 |
| | 3 | Benny Barnes | at Washington • 1971 |
| | | | |
| Season |
| 1. | 9 | Phil Moffatt | 1930 |
| | 9 | Bobby Garrett | 1953 |
| 3. | 8 | Phil Moffatt | 1929 |
| | 8 | Benny Barnes | 1971 |
| | 8 | Toi Cook | 1986 |
| 6. | 7 | Jim Kaffen | 1972 |
| 7. | 6 | Steve Murray | 1972 |
| | 6 | Brad Humphreys | 1987 |
| | 6 | Vaughn Bryant | 1992 |
| | 6 | Tim Smith | 1998 |
| | 6 | Tim Smith | 1999 |
| | 6 | Ed Reynolds | 2012 |
| | | | |
| Career |
| 1. | 20 | Phil Moffatt | 1929-31 |
| 2. | 17 | Toi Cook | 1983-86 |
| 3. | 16 | Tim Smith | 1996-99 |
| 4. | 14 | Brad Humphreys | 1985-87 |
| 5. | 11 | Dick Ragsdale | 1962-64 |
| | 11 | Leroy Pruitt | 1993-96 |
| 7. | 10 | John Guillory | 1964-66 |
| | 10 | Vaughn Bryant | 1990-93 |
| | 10 | Bo McNally | 2006-09 |
| 10. | 9 | Bobby Garrett | 1951-53 |
| | 9 | Benny Barnes | 1970-71 |
| | 9 | Steve Murray | 1970-72 |
| | 9 | Randy Poltl | 1971-73 |
| | 9 | Rich Walters | 1974-76 |
| | 9 | Charles Hutchings | 1980-83 |
| | 9 | Tank Williams | 1998-01 |
| | 9 | Oshiomogho Atogwe | 2001-04 |
| | | | |
| Longest Interception Return |
| Game |
| 1. | 95 | Tom Work | vs. Occidental • 1926 |
